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Gendre’s Fixative

Gendre’s Fixative

Formula

MaterialAmount
Picric acid, sat. ethanolic800mL
Formalin, concentrated150mL
Acetic acid, glacial50mL

Description

Gendre’s fixative may be thought of as an alcoholic Bouin’s fluid. It may be recommended when glycogen is the target element. Both ethanol and picric acid enhance the preservation of glycogen either by trapping it within protein or by precipitation. Tissues should not be left in it for extended periods.

Safety Note

Prior to handling any chemical, consult the Safety Data Sheet (SDS) for proper handling and safety precautions.

References

  1. Gray, Peter. (1954)
    The Microtomist’s Formulary and Guide.
    Originally published by: The Blakiston Co.
    Republished by: Robert E. Krieger Publishing Co.
    Citing:
    Gendre, (1937)
    Bulletin d’histologie appliquée à la physiologie et à la pathologie et de technique microscopique. v. 14, p. 262.