Thioflavine S

Thioflavine S
Property Data
Common name
Suggested name
Other names
C.I. number
C.I. name
Class
Ionisation
Solubility aqueous
Solubility ethanol
Absorption maximum
Colour
Empirical formula
Formula weight
Thioflavine S
Thioflavine S

49010
Direct yellow 7
Thiazole
Acid
Very
Soluble
374
Yellow


The structural formula above was located via the Internet, and is of the major component of the dye, according to Wu and coworkers. It is a fluorescent dye and is a mixture, one component of which demonstrates amyloid. Conn states that thioflavine S is made from primuline by methylation and sulphonation.

 

Reference
R. D. Lillie.
Conn's Biological Stains
Williams & Wilkins, Baltimore, MD., U.S.A.

Wu, C., Wei, J.. Gao. Y and Wang. Y.,
Dibenzothiazoles as novel amyloid-imaging agents,
Bioorganic and Medicinal Chemistry, v15, pp.2789-2796
Elsevier, U.S.A.

 


 

 

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