Tartrazine is often used saturated in cellosolve (2-ethoxy ethanol) to differentiate other (red) acid dyes while staining the tissue from which the dye has been removed yellow. Lendrum's phloxine tartrazine method for Paneth cell granules is a good example. It is rarely employed for other purposes, although it contrasts very well as a background stain with nuclei stained by nuclear fast red.